Opportunity Information: Apply for RFA HD 18 102
The grant opportunity "Advancing the Science of Multipurpose Technology for the Prevention of HIV and Unintended Pregnancy (R43/R44)" is a National Institutes of Health (NIH) Small Business Innovation Research (SBIR) funding initiative aimed at accelerating the development of multipurpose prevention technologies (MPTs) for adolescent girls and young women. The central goal is to support small businesses in creating new and innovative product concepts that combine HIV prevention with contraception in a single modality, with an emphasis on novel combinations of active agents and delivery systems. The underlying public health rationale is that HIV infection and unintended pregnancy remain two high-burden, often overlapping risks for young women worldwide, and solutions that address both needs at once could be more practical, acceptable, and consistently used than separate single-purpose products.
This opportunity is structured under the SBIR R43/R44 mechanism, which is designed to move technologies from early proof-of-concept through further development toward commercialization. In practice, that means applicants are expected to propose research and development efforts that build credible, product-oriented evidence that a combined HIV and pregnancy prevention approach can work safely and effectively, and that it can be delivered in a way real users will actually adopt. The solicitation highlights that combination prevention modalities may improve adherence, particularly among younger populations, because they simplify decision-making and reduce the burden of managing multiple products. A successful MPT concept under this program would ideally provide reliable protection against HIV while also offering effective contraception, reflecting the real-life needs of young women who may be at risk for infection and simultaneously want to avoid pregnancy.
Eligibility is limited to small businesses, consistent with SBIR rules, and the program explicitly restricts foreign participation at the applicant level. Non-domestic (non-U.S.) entities (foreign institutions) are not eligible to apply, and non-domestic components of U.S. organizations are also not eligible to apply. However, the announcement notes that "foreign components," as defined in the NIH Grants Policy Statement, may be permitted in some cases, which generally means certain discrete elements of the project can be carried out abroad when they are well-justified and compliant with NIH policy, even though the applicant organization itself must be U.S.-based and eligible.
Key administrative details from the source information include the Funding Opportunity Number RFA-HD-18-102 and the CFDA number 93.865. The sponsor is NIH, the funding instrument is a grant, and the activity category is listed under Health, Income Security and Social Services. The original closing date for applications was 2018-01-22, and the opportunity record shows a creation date of 2017-11-22. While the provided listing does not specify an award ceiling or the expected number of awards, the intent is clearly to stimulate innovation by supporting early-stage and developmental R and D efforts that could yield viable MPT product candidates for the prevention of HIV and unintended pregnancy in adolescent girls and young women.Apply for RFA HD 18 102
- The National Institutes of Health in the health, income security and social services sector is offering a public funding opportunity titled "Advancing the Science of Multipurpose Technology for the Prevention of HIV and Unintended Pregnancy (R43/R44)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865.
- This funding opportunity was created on 2017-11-22.
- Applicants must submit their applications by 2018-01-22. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Eligible applicants include: Small businesses.
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| Funding Opportunity |
|---|
| Advancing the Science of Multipurpose Technology for the Prevention of HIV and Unintended Pregnancy (R41/R42) Apply for RFA HD 18 101 Funding Number: RFA HD 18 101 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| Translational Research in Pediatric and Obstetric Pharmacology and Therapeutics (R21 Clinical Trial Optional) Apply for PAR 18 214 Funding Number: PAR 18 214 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $200,000 |
| Translational Research in Pediatric and Obstetric Pharmacology and Therapeutics (R01 Clinical Trial Optional) Apply for PAR 18 215 Funding Number: PAR 18 215 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| NICHD Research Education Programs (R25 Clinical Trial Optional) Apply for PAR 18 217 Funding Number: PAR 18 217 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $150,000 |
| NICHD Small Grant Program (R03 - Clinical Trial Optional) Apply for PA 18 481 Funding Number: PA 18 481 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $50,000 |
| NICHD Research Project Grant (R01 - Clinical Trial Required) Apply for PA 18 480 Funding Number: PA 18 480 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| NICHD Exploratory/Developmental Research Grant (R21 - Clinical Trial Optional) Apply for PA 18 482 Funding Number: PA 18 482 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $200,000 |
| The Role of Stem/Progenitor Cells in the Pathogenesis and Treatment of Gynecologic Disorders (R01 - Clinical Trial Optional) Apply for RFA HD 19 013 Funding Number: RFA HD 19 013 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $499,999 |
| Studies in Neonatal and Pediatric Resuscitation (R01 Clinical Trial Optional) Apply for PA 18 485 Funding Number: PA 18 485 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| Studies in Neonatal and Pediatric Resuscitation (R03 - Clinical Trial Optional) Apply for PA 18 491 Funding Number: PA 18 491 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $50,000 |
| Non-Invasive Diagnostics to Improve Gynecologic Health (R43/R44 - Clinical Trial Optional) Apply for RFA HD 19 006 Funding Number: RFA HD 19 006 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| Drug Repurposing for Conditions Affecting Neonates and Pregnant Women (R01 - Clinical Trial Optional) Apply for PAR 18 506 Funding Number: PAR 18 506 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| Discovery of Molecular Targets for Pregnancy-Related/Induced Diseases and Development of Therapeutics to Prevent/Treat These Diseases (R01 - Clinical Trial Optional) Apply for PAR 18 511 Funding Number: PAR 18 511 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| Human-Animal Interaction (HAI) Research (R21 - Clinical Trial Optional) Apply for PAR 18 650 Funding Number: PAR 18 650 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $200,000 |
| Human-Animal Interaction (HAI) Research (R03 - Clinical Trial Optional) Apply for PAR 18 649 Funding Number: PAR 18 649 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $50,000 |
| Developmental Pharmacodynamics and Models of Drug Effects in Pediatrics (R03 Clinical Trial Optional) Apply for PA 18 687 Funding Number: PA 18 687 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $50,000 |
| Innovative Therapies and Tools for Screenable Disorders (R01 Clinical Trial Optional) Apply for PAR 18 689 Funding Number: PAR 18 689 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
| Innovative Therapies and Tools for Screenable Disorders (R03 Clinical Trial Optional) Apply for PAR 18 690 Funding Number: PAR 18 690 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $50,000 |
| Innovative Therapies and Tools for Screenable Disorders (R21 Clinical Trial Optional) Apply for PAR 18 691 Funding Number: PAR 18 691 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: $200,000 |
| Developmental Pharmacodynamics and Models of Drug Effects in Pediatrics (R01 Clinical Trial Optional) Apply for PA 18 688 Funding Number: PA 18 688 Agency: National Institutes of Health Category: Health, Income Security and Social Services Funding Amount: Case Dependent |
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