Opportunity Information: Apply for RFA DA 20 002
The funding opportunity titled "Limited Competition for Adolescent Brain Cognitive Development (ABCD) Study - Linked Research Project Sites (Collaborative U01 Clinical Trial Not Allowed)" is a National Institutes of Health (NIH) cooperative agreement aimed at continuing and expanding the Adolescent Brain Cognitive Development (ABCD) Study through a set of linked research project sites. It is being issued under the Collaborative Research on Addiction at NIH (CRAN) effort and is led by the National Institute on Drug Abuse (NIDA) in partnership with several other NIH Institutes and Centers, including NIAAA, NICHD, NIMH, NIMHD, NINDS, OBSSR, and NCI. The overall purpose is to support a coordinated, nationwide research infrastructure that can follow a large cohort of young people over time and generate harmonized, high-quality data on how the brain and behavior develop from late childhood into adolescence and early adulthood, with particular relevance to substance use and addiction-related outcomes.
At its core, this opportunity is designed to fund research project sites that contribute directly to a multisite, multi-modal, longitudinal cohort study. "Longitudinal" here means participants are followed repeatedly across many years rather than assessed once, allowing researchers to see how changes unfold within individuals. The ABCD framework is "multi-modal," indicating that it integrates multiple types of measures rather than relying on a single data source. In practical terms, that typically means combining brain-focused measures with behavioral, developmental, environmental, and health-related assessments so that biological development can be interpreted alongside experiences, mental health, and social context. The cohort begins at approximately ages 9 to 10, capturing a developmental window just before or at the beginning of many adolescent transitions, and then follows participants through adolescence into early adulthood, when trajectories related to cognition, emotion, risk-taking, and substance exposure can become more distinct.
The mechanism is a U01 cooperative agreement, which signals that NIH expects substantial involvement in the coordination and oversight of the project compared with a traditional research grant. Rather than a collection of independent studies, the intent is a tightly organized network of sites operating under shared protocols and centralized coordination so that data are comparable across locations and time. The title also specifies "Clinical Trial Not Allowed," meaning applications should not propose clinical trials as defined by NIH; the work is intended to be observational and developmental in nature, focused on tracking and understanding outcomes rather than testing interventions.
This is a limited competition, and eligibility is constrained to current primary awardees, reflecting the fact that NIH is seeking continuity of established ABCD infrastructure and expertise rather than opening competition broadly to new sites. Eligible applicant organizations are listed as public and state-controlled institutions of higher education, consistent with the large-scale, research-intensive requirements of running a long-term cohort site. The award period for this new phase is expected to be extended to seven years, which underscores the long-horizon commitment needed to follow youth through multiple developmental stages, retain participants, maintain consistent measurement, and preserve data quality across repeated assessments.
Administratively, the opportunity is categorized as discretionary funding and uses a cooperative agreement funding instrument. It was created on April 3, 2019, with an original closing date of July 24, 2019. The expected number of awards is 21, indicating a sizeable network of funded sites. The listing shows an award ceiling of 0, which typically reflects that a single fixed maximum amount is not specified in the summary fields and that actual budgets are determined through NIH review and negotiation based on the proposed scope, required infrastructure, and the cooperative agreement structure.
In summary, this announcement supports a coordinated national set of ABCD linked research project sites under CRAN, focused on prospectively mapping brain and behavioral development beginning around ages 9 to 10 and continuing through adolescence into early adulthood. It emphasizes standardized, collaborative, multi-modal data collection across many locations, excludes clinical trials, limits competition to existing primary awardees, and extends support for a seven-year period to sustain the long-term cohort and its scientific value.Apply for RFA DA 20 002
- The Department of Health and Human Services, National Institutes of Health in the education, health, income security and social services sector is offering a public funding opportunity titled "Limited Competition for Adolescent Brain Cognitive Development (ABCD) Study - Linked Research Project Sites (Collaborative U01 Clinical Trial Not Allowed)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.242, 93.273, 93.279, 93.307, 93.313, 93.399, 93.853, 93.865.
- This funding opportunity was created on Apr 03, 2019.
- Applicants must submit their applications by Jul 24, 2019. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 21 candidate(s).
- Eligible applicants include: Public and State controlled institutions of higher education.
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Applicants also applied for:
Applicants who have applied for this opportunity (RFA DA 20 002) also looked into and applied for these:
| Funding Opportunity |
|---|
| Data Coordinating and Operations Center for the ECHO IDeA States Pediatric Clinical Trials Network - 2 (U24 - Clinical Trial Required -Infrastructure) Apply for RFA OD 19 025 Funding Number: RFA OD 19 025 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| HEAL Initiative: Pragmatic and Implementation Studies for the Management of Pain to Reduce Opioid Prescribing (PRISM) (UG3/UH3, Clinical Trials Optional) Apply for RFA AT 20 004 Funding Number: RFA AT 20 004 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Exploratory Team-Research BRAIN Circuit Programs - eTeamBCP (U01 Clinical Trials Optional) Apply for RFA NS 20 029 Funding Number: RFA NS 20 029 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| Martin Delaney Collaboratory for Pediatric HIV Cure Research (UM1 Clinical Trial Not Allowed) Apply for RFA AI 20 036 Funding Number: RFA AI 20 036 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $3,500,000 |
| BRAIN Initiative: Theories, Models and Methods for Analysis of Complex Data from the Brain (R01 Clinical Trial Not Allowed) Apply for RFA EB 20 002 Funding Number: RFA EB 20 002 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $250,000 |
| Emergency Awards: Automatic Detection and Tracing of SARS-CoV-2 (U01 Clinical Trial Not Allowed) Apply for RFA OD 20 014 Funding Number: RFA OD 20 014 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $300,000 |
| Emergency Awards RADx-RAD: Screening for COVID-19 by Electronic-Nose Technology (SCENT) (U18 Clinical Trial Not Allowed) Apply for RFA OD 20 017 Funding Number: RFA OD 20 017 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Targeted BRAIN Circuits Projects- TargetedBCP (R01 Clinical Trial Not Allowed) Apply for RFA NS 21 013 Funding Number: RFA NS 21 013 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Targeted BRAIN Circuits Planning Projects TargetedBCPP (R34 Clinical Trials Not Allowed) Apply for RFA NS 21 014 Funding Number: RFA NS 21 014 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $225,000 |
| Small Research Grants for Analyses of Data for the Gabriella Miller Kids First Data Resource (R03) Apply for PAR 16 348 Funding Number: PAR 16 348 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: $200,000 |
| BRAIN Initiative: Development and Validation of Novel Tools to Analyze Cell-Specific and Circuit-Specific Processes in the Brain (R01) Apply for RFA MH 17 220 Funding Number: RFA MH 17 220 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Non-Invasive Neuromodulation - Mechanisms and Dose/Response Relationships for Targeted CNS Effects (R01) Apply for RFA MH 17 245 Funding Number: RFA MH 17 245 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Non-Invasive Neuromodulation - New Tools and Techniques for Spatiotemporal Precision (R01) Apply for RFA MH 17 240 Funding Number: RFA MH 17 240 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative Fellows: Ruth L. Kirschstein National Research Service Award (NRSA) Individual Postdoctoral Fellowship (F32) Apply for RFA MH 17 250 Funding Number: RFA MH 17 250 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Data Archives for the BRAIN Initiative (R24) Apply for RFA MH 17 255 Funding Number: RFA MH 17 255 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Standards to Define Experiments Related to the BRAIN Initiative (R24) Apply for RFA MH 17 256 Funding Number: RFA MH 17 256 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Integration and Analysis of BRAIN Initiative Data (R24) Apply for RFA MH 17 257 Funding Number: RFA MH 17 257 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: New Technologies and Novel Approaches for Large-Scale Recording and Modulation in the Nervous System (U01) Apply for RFA NS 17 003 Funding Number: RFA NS 17 003 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Optimization of Transformative Technologies for Large Scale Recording and Modulation in the Nervous System (U01) Apply for RFA NS 17 004 Funding Number: RFA NS 17 004 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
| BRAIN Initiative: Next-Generation Invasive Devices for Recording and Modulation in the Human Central Nervous System (U44) Apply for RFA NS 17 007 Funding Number: RFA NS 17 007 Agency: National Institutes of Health Category: Education, Health, Income Security and Social Services Funding Amount: Case Dependent |
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